[Favourable outcome after fetoscopic laser surgery for twin-twin transfusion syndrome: experience of an emerging
A Delabaere1, M Accoceberry, J Niro
1Pôle gynécologie-obstétrique-reproduction humaine, CHU Clermont-Ferrand, Hôtel-Dieu, boulevard Léon-Malfreyt, Clermont-Ferrand, France.
Objectives:
Our objective was to report perinatal outcome during the first three years of an emerging centre for laser photocoagulation in twin-twin transfusion syndrome (TTTS) and to compare with outcome observed earlier in the same centre when management consisted in recurrent amniodrainage.
Patients And Methods:
We conducted a single centre retrospective study. We compared perinatal outcome of 19 consecutive cases of mid trimester TTTS managed by amniodrainage over a 10-year period with 49 cases of TTTS managed by laser photocoagulation over a 3-year period.
Results:
Laser photocoagulation increased survival rate at birth (P=0.02) and at postnatal day 28 (P=0.01). Neurologic and cardiologic complications did not differ significantly (P=0.5 and P=0.3 respectively). We observed a significant increase in survival of the donor after laser coagulation at birth (P=0.04).
Discussion And Conclusion:
Our study demonstrated better outcome after laser photocoagulation. Early results of an emerging centre appeared comparable to those of more experienced centres.
