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Updated: Jun 1, 2026

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage
Published on: November 4, 2010
[Risk factors for anastomotic leakage after anterior resection for rectal cancer]
Chao Feng1, Ruo-quan Yao, Fei-zhou Huang
1Department of General Surgery, Third Xiangya Hospital of Central South University, Changsha 410013, China. fccc.1234@yahoo.cm.cn
Objective:
To identify the risk factors associated with anastomotic leakage following an anterior resection for rectal cancer.
Methods:
Between June, 1999 and June, 2009, 628 patients underwent anterior resection for rectal cancer. A retrospective study of the cases was performed to identify the risk factors for anastomotic leakage following the resection.
Results:
The overall incidence rate of anatomic leak was 8.6% (54/628) in these patients. A low albumin level (less than 35 g/L), diabetes, absence of a protective stoma, a distance less than 7 cm from the tumor to the anal edge, and a tumor diameter over 5 cm were identified as the risk factors for anastomotic leakage after anterior resection.
Conclusion:
For patients at a high risk for anastomotic leakage, a protective stoma can significantly decrease the rate of clinical leaks and subsequent reoperation after low anterior resection for rectal cancer.
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