Related Experiment Video
Updated: Jun 1, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Risk factors for interruption to soft contact lens wear in children and young adults
Heidi Wagner1, Robin L Chalmers, G Lynn Mitchell
1College of Optometry, Nova Southeastern University, Ft. Lauderdale, Florida 33328, USA. wagner@nova.edu
Purpose:
The purpose of this study was to describe age and other risk factors for ocular events that interrupt soft contact lens (SCL) wear in youth.
Methods:
A retrospective chart review of SCL wearers aged 8 to 33 years at the first observed visit was conducted at six academic eye care centers in North America. Data were extracted from all visits during the observation period (>3 years). Clinical records that documented conditions resulting in an interruption of SCL wear "events" were scanned, masked for age and SCL parameters, and then adjudicated to consensus diagnosis. Generalized estimating equations were used to examine the effect of selected covariates, including age, on the risk of an event.
Results:
Chart review of 3549 SCL wearers yielded 522 events among 426 wearers (12%). The risk of an event increased from ages 8 to 18 years, showed modest increases between ages 19 and 25 years, and then began to decline after age 25 years. New lens wearers (<1 year) were less likely to experience events (p = 0.001). Lens replacement schedule and material were also predictive of interruptions to SCL wear with the lowest risk in daily replacement and hydrogel lens wearers (both p < 0.0001).
Conclusions:
These results suggest that the risk of events that interrupt SCL wear peaks in late adolescence and early adulthood and reflects risk factors identified in prospective contact lens studies. Relative to older teens and young adults, patients younger than 14 years presented with significantly fewer events resulting in interrupted lens wear.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Photoreceptors and Visual Pathways
Factors Affecting Illness
For instance, risk factors are connected to illness, disability,...
Drug Toxicity: Risk factors
Accessory Structures of the Eye
Microbiome of the Eye

