Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Where Is the Client in Client-Centered Care? Centering the Experiences of Integrated Care Among Black Women in Public Health Settings.

Healthcare (Basel, Switzerland)·2026
Same author

A collective agenda: A qualitative study on Exercise is Medicine® On Campus gold-level institutions.

Preventive medicine reports·2024
Same author

Systemic Venous Air Emboli After Emergent Hyperbaric Therapy for Carbon Monoxide Poisoning.

The American journal of case reports·2023
Same author

Omental Torsion and Infarction Secondary to Omental Hernia in the Right Inguinal Canal.

Taehan Yongsang Uihakhoe chi·2022
Same author

Role of multidetector computed tomography in patients with acute infectious colitis.

World journal of clinical cases·2022
Same author

"In Our Own Little World": Invisibility of the Social and Ethical Dimension of Engineering Among Undergraduate Students.

Science and engineering ethics·2021

Related Experiment Video

Updated: Jun 1, 2026

A New Clarification Method to Visualize Biliary Degeneration During Liver Metamorphosis in Sea Lamprey (Petromyzon marinus)
07:03

A New Clarification Method to Visualize Biliary Degeneration During Liver Metamorphosis in Sea Lamprey (Petromyzon marinus)

Published on: June 6, 2014

Liver flukes: the malady neglected.

Jae Hoon Lim1

  • 1Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea. jhlim@smc.samsung.co.kr

Korean Journal of Radiology
|May 24, 2011
PubMed
Summary

Liver fluke disease, caused by parasitic worms from raw fish, leads to chronic bile duct inflammation. This infection affects millions globally and is linked to severe complications like bile duct cancer.

Keywords:
CholangiocarcinomaCholangiocarinogenesisClonorchiasisFoodborne parasiteLiver flukesOpisthorchiasis

More Related Videos

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
12:05

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

Published on: January 14, 2018

Related Experiment Videos

Last Updated: Jun 1, 2026

A New Clarification Method to Visualize Biliary Degeneration During Liver Metamorphosis in Sea Lamprey (Petromyzon marinus)
07:03

A New Clarification Method to Visualize Biliary Degeneration During Liver Metamorphosis in Sea Lamprey (Petromyzon marinus)

Published on: June 6, 2014

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
12:05

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

Published on: January 14, 2018

Area of Science:

  • Parasitology
  • Hepatology
  • Public Health

Background:

  • Liver fluke disease is a chronic parasitic inflammatory condition affecting the bile ducts.
  • Infection results from consuming raw fish contaminated with liver flukes, primarily Clonorchis sinensis, Opisthorchis viverrini, and Opisthorchis felineus.

Purpose of the Study:

  • To highlight the chronic nature and public health impact of liver fluke infections.
  • To underscore the association between liver fluke disease and severe clinical outcomes, including cholangiocarcinoma.

Main Methods:

  • This study is a review of existing literature on liver fluke disease.
  • Information on parasitic species, infection routes, pathogenesis, clinical manifestations, and complications was synthesized.

Main Results:

  • Adult flukes reside in bile ducts for 20-30 years, causing chronic inflammation, hyperplasia, fibrosis, and dilatation.
  • While most infections are asymptomatic, heavy burdens can cause malaise and abdominal discomfort.
  • Complications include gallstones, recurrent pyogenic cholangitis, and a significantly increased risk of cholangiocarcinoma.

Conclusions:

  • Liver fluke infection is a significant food-borne disease affecting approximately 35 million people worldwide.
  • The high incidence of cholangiocarcinoma in endemic regions is strongly linked to liver fluke prevalence.
  • Given its public health impact and severe consequences, liver fluke infection requires continued attention and prevention efforts.