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Related Concept Videos

Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Transient ischemic attack and stroke can be differentiated by analyzing the diffusion tensor imaging.

Tong Tong1, Yao Zhenwei, Feng Xiaoyuan

  • 1Department of Radiology, Fudan University Shanghai Cancer Center, The Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. t983352@126.com

Korean Journal of Radiology
|May 24, 2011
PubMed
Summary
This summary is machine-generated.

Fractional anisotropy ratio (rFA) and corticospinal tract (CST) involvement effectively differentiate transient ischemic attack (TIA) from minor stroke. This analysis may predict long-term patient recovery and disability.

Keywords:
Diffusion tensor imagingMagnetic resonance imagingStrokeTransient ischemic attack

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Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Transient ischemic attack (TIA) and minor stroke share similar initial symptoms, making differentiation challenging.
  • Accurate diagnosis is crucial for appropriate treatment and prognosis.
  • Advanced neuroimaging techniques may offer better diagnostic capabilities.

Purpose of the Study:

  • To differentiate between transient ischemic attack (TIA) and minor stroke.
  • To utilize fractional anisotropy (FA) and 3D fiber tractography for diagnostic distinction.
  • To explore the potential of these methods in predicting patient outcomes.

Main Methods:

  • Acquired clinical data, conventional MRI, DWI, and DTI for 45 TIA and 33 minor stroke patients.
  • Calculated fractional anisotropy ratio (rFA) between lesion and contralateral tissue.
  • Analyzed spatial relationship between lesions and corticospinal tract (CST), comparing lesion sizes.

Main Results:

  • 49% of TIA patients showed focal abnormalities on DWI.
  • Stroke patients had significantly lower rFA (0.71 ± 0.29) than TIA patients (1.05 ± 0.37).
  • CST involvement was observed in most stroke lesions but only 32% of TIA lesions; CST injury scores were significantly lower in TIA patients (3.25 ± 1.75) vs. stroke patients (8.80 ± 2.39).

Conclusions:

  • rFA analysis and CST involvement assessment can distinguish TIA from minor stroke.
  • This neuroimaging approach may enable more accurate prediction of long-term recovery and disability.
  • Further research can validate these findings for clinical application.