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Updated: Jun 1, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Induced hypothermia as a neuroprotectant in post-cardiac arrest
Mohi E Alkadri1, Paul McMullan
1Department of Cardiology, Ochsner Clinic Foundation, New Orleans, LA.
Abstract:
Survivors of out-of-hospital cardiac arrest frequently suffer devastating effects from anoxic brain injury. Therapeutic hypothermia is the first therapy to show benefit in improving survival as well as limiting neurologic injury. We review the data supporting the use of therapeutic hypothermia in this patient population, the pathophysiologic basis of its neuroprotectant effects, the methods of hypothermic induction, and the clinical application.
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