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Clinical course of vesicoureteral reflux in patients with hypospadias

Kwang Hyun Kim1, Hye Young Lee, Young Jae Im

  • 1Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea. swhan@yuhs.ac

International Journal of Urology : Official Journal of the Japanese Urological Association
|May 25, 2011
PubMed

Insights

Vesicoureteral reflux (VUR) is more common in hypospadias patients, especially infants. However, routine screening for VUR is not recommended as it typically resolves on its own.

Area of Science:

  • Pediatric Urology
  • Nephrology

Background:

  • Vesicoureteral reflux (VUR) is more prevalent in children with hypospadias compared to healthy peers.
  • Understanding the incidence and natural history of VUR in this population is crucial for appropriate management.

Purpose of the Study:

  • To determine the prevalence of VUR in patients undergoing hypospadias repair.
  • To investigate the clinical course and resolution rates of VUR in this cohort.

Main Methods:

  • Intraoperative cystography was performed in 338 hypospadias repair patients.
  • VUR detection was followed by dimercaptosuccinic acid renal scans and voiding cystourethrography (VCUG) as indicated.
  • Age and hypospadias severity were assessed alongside VUR presence.

Main Results:

  • VUR was detected in 12.1% of patients, with a higher prevalence (21.8%) in infants under one year.
  • VUR prevalence was significantly associated with younger age but not hypospadias type.
  • Most VUR cases were low-grade, and renal scarring was infrequent; VUR resolved or improved in all follow-up cases.

Conclusions:

  • While VUR is more common in hypospadias patients, routine screening is not necessary.
  • The high spontaneous resolution rate and low incidence of renal scarring suggest conservative management is appropriate.
Abstract

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