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Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay
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Insulin receptor and cancer

Antonino Belfiore1, Roberta Malaguarnera

  • 1Endocrinology Unit, Department of Clinical and Experimental Medicine, University Magna Graecia of Catanzaro, Campus Universitario, località Germaneto, 88100 Catanzaro, Italy. belfiore@unicz.it

Endocrine-Related Cancer
|May 25, 2011
PubMed
Summary

Obesity and type 2 diabetes increase cancer risk by promoting hyperinsulinemia and insulin receptor (IR) signaling. Targeting the IR-A pathway is crucial for future cancer therapies to inhibit tumor growth without metabolic side effects.

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