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Cystic Fibrosis: Pathogenesis

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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Updated: Jun 1, 2026

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

Diffuse cystic lung disease at high-resolution CT.

Danielle M Seaman¹, Cristopher A Meyer, Matthew D Gilman

¹Department of Radiology, Duke University Medical Center, Box 3808 DUMC, Durham, NC 27710, USA.

AJR. American Journal of Roentgenology

|May 25, 2011

Summary

This summary is machine-generated.

High-resolution CT (HRCT) helps identify various lung diseases presenting as air cysts. Recognizing HRCT patterns aids in diagnosing interstitial lung diseases beyond common conditions like lymphangioleiomyomatosis.

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

Radiology
Pulmonology
Medical Imaging

Background:

Air cysts in the lungs can be indicative of various interstitial lung diseases.
High-resolution computed tomography (HRCT) is a key imaging technique for evaluating lung parenchyma.
Understanding the diverse appearances of cystic lung disease on HRCT is crucial for diagnosis.

Purpose of the Study:

To illustrate and describe the spectrum of diseases associated with pulmonary air cysts.
To highlight the utility of HRCT in diagnosing cystic lung disease.
To enhance the differential diagnosis of interstitial lung diseases with cystic patterns.

Main Methods:

Review of HRCT findings in patients with pulmonary air cysts.
Correlation of imaging findings with clinical and pathological data.
Description of characteristic HRCT features for various etiologies of cystic lung disease.

Main Results:

Pulmonary air cysts are associated with a spectrum of interstitial lung diseases.
Lymphangioleiomyomatosis and Langerhans cell histiocytosis are common causes, but other entities are increasingly recognized.
Specific HRCT patterns can suggest particular underlying diseases.

Conclusions:

HRCT is essential for evaluating interstitial and cystic lung diseases.
Awareness of the diverse HRCT manifestations of cystic lung disease improves diagnostic accuracy.
HRCT findings can help differentiate between various causes of cystic lung disease, aiding in diagnosis.