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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

Ned Van Eps1, Anita M Preininger, Nathan Alexander

  • 1Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-7008, USA.

Proceedings of the National Academy of Sciences of the United States of America
|May 25, 2011
PubMed

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