Effects of Cynodon dactylon on Stress-Induced Infertility in Male Rats

Area of Science:

• Ethnobotany
• Reproductive Biology
• Pharmacology

Background:

• Cynodon dactylon (Family: Poaceae) is a widely distributed plant with mythological significance in India.
• Stress is a significant factor contributing to male infertility, impacting sexual function and reproductive health.
• Traditional medicine often utilizes plants for their therapeutic properties, including aphrodisiac and fertility-enhancing effects.

Purpose of the Study:

• To investigate the efficacy of Cynodon dactylon extract in mitigating stress-induced male sexual dysfunction and infertility.
• To evaluate the restorative effects of Cynodon dactylon on various parameters of male reproductive health under stress conditions.

Main Methods:

• Male infertility was induced in rats using immobilization stress.
• The effects of methanolic extract of Cynodon dactylon were assessed through sexual behavior observations, sexual performance tests, and measurement of seminal vesicle fructose content.
• Epididymal sperm concentration and histopathological examinations of accessory sexual organs were also conducted.

Main Results:

• Methanolic extract of Cynodon dactylon significantly improved sexual behavior and performance in stressed rats.
• Treatment with the extract led to increased fructose content in seminal vesicles and higher epididymal sperm concentration.
• Histopathological examinations indicated a positive effect on accessory sexual organs and overall body weight.

Conclusions:

• Active constituents within the methanolic extract of Cynodon dactylon possess potent aphrodisiac and male fertility-promoting activities.
• Cynodon dactylon extract effectively counteracts the detrimental effects of stress on male sexual function and reproductive capacity.
• This study supports the traditional use of Cynodon dactylon and suggests its potential as a natural therapeutic agent for male infertility.