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Updated: Jun 1, 2026

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
Published on: November 10, 2017
Programmed cell-death and its control in the development of adult T-cell leukemia - hypothesis
H Tsuda1, R Huang, K Takatsuki
1KUMAMOTO UNIV,SCH MED,DEPT INTERNAL MED 2,KUMAMOTO 860,JAPAN.
Abstract:
Despite the progress in virological and molecular studies on human T-cell leukaemia virus (HTLV-1), there still exist enigmas in biological and clinical features of adult T-cell leukaemia/lymphoma (ATL). They include the way of the development of ATL clones, the role of interleukin-2 (IL-2) receptors on the tumour cells and spontaneous fluctuation of the clinical activity frequently observed in chronic type of the disease. To elucidate these enigmas, based on our recent experimental data, we would like to present a model of the development of ATL clones from: the view point of programmed cell death (PCD) and its control.
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