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Updated: Jun 1, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Influence of inflammatory reaction in primary fallopian-tube carcinoma (stage-I and stage-ii)
1UNIV VIENNA,DEPT CLIN PATHOL,VIENNA,AUSTRIA. HANUSCH HOSP,DEPT OBSTET & GYNECOL,VIENNA,AUSTRIA. GRAZ UNIV,DEPT OBSTET & GYNECOL,GRAZ,AUSTRIA. DEPT OBSTET & GYNECOL,SALZBURG,AUSTRIA. UNIV VIENNA,DEPT OBSTET & GYNECOL,VIENNA,AUSTRIA. SMZ OST,BOLTZMANN INST SURG ONCOL,VIENNA,AUSTRIA.
Abstract:
A retrospective evaluation of 68 Fallopian tube carcinomas (FTC) of a period of ten years (1980-1990) in stage I and II was performed. The aim of this study was to evaluate the prognostic impact of various factors. 68 cases were investigated for the prognostic influence of mitotic activity, degree of nuclear anaplasia and inflammatory reaction. Histological grading (p=0.08), and inflammatory reaction (p=0.003) showed to have a prognostic impact for survival in univariate analysis. Whereas, mitotic activity did not show any statistically significant influence. 47 (69%) tissue samples showed a positive inflammatory reaction which correlated with a significantly better outcome compared with tumors without this feature. However, this influence was proved in multivariate analysis for inflammatory reaction only (p=0.01). Although no data on the influence of the inflammatory reaction on prognosis in FTC has been published up to now, we can state that the determination of this factor can be useful for prognosis in this rare but highly aggressive tumor.
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