Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Flavonoid-rich foods, genetic risk, and female breast cancer risk: a prospective cohort study.

NPJ breast cancer·2026
Same author

Plasma proteome-metabolome signatures enable non-invasive early detection and lymph node risk stratification in breast cancer.

Molecular cancer·2026
Same author

Advanced colorectal neoplasia and colorectal cancer in metabolic dysfunction-associated steatotic liver disease.

Journal of advanced research·2026
Same author

A Meta-Analysis-Based Risk Score for Predicting Radiation Pneumonitis After Thoracic Radiation Therapy for Lung Cancer.

International journal of radiation oncology, biology, physics·2026
Same author

Cross-Distribution Diffusion Priors-Driven Iterative Reconstruction for Sparse-View CT.

IEEE transactions on medical imaging·2026
Same author

Modernizing drug development and ensuring global equity in the organoid revolution.

Communications biology·2026

Related Experiment Video

Updated: Jun 1, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Highly-ordered, 3D petal-like array for surface-enhanced Raman scattering.

Chuang Qian1, Chao Ni, Wenxuan Yu

  • 1National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Institute of Microelectronics, Peking University, Beijing, 100871, P.R. China.

Small (Weinheim an Der Bergstrasse, Germany)
|May 25, 2011
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel 3D petal-like arrayed structure (3D PLAS) for surface-enhanced Raman scattering (SERS) substrates. This easily fabricated SERS substrate offers high reproducibility and significant signal enhancement for sensitive chemical detection.

More Related Videos

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications
06:15

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Published on: June 16, 2023

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection
03:33

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Published on: November 17, 2023

Related Experiment Videos

Last Updated: Jun 1, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications
06:15

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Published on: June 16, 2023

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection
03:33

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Published on: November 17, 2023

Area of Science:

  • Materials Science
  • Nanotechnology
  • Spectroscopy

Background:

  • Surface-enhanced Raman scattering (SERS) shows great potential for chemical analysis.
  • Fabricating reliable and highly sensitive SERS substrates remains a significant challenge.
  • Existing methods often struggle with reproducibility and cost-effectiveness.

Purpose of the Study:

  • To propose a simple and reproducible method for fabricating a novel 3D SERS substrate.
  • To investigate the SERS performance of the fabricated substrate.
  • To explore the influence of key fabrication parameters on SERS enhancement.

Main Methods:

  • Fabrication of a 3D petal-like arrayed structure (3D PLAS) using self-assembled silica nanoparticles.
  • Anisotropic etching of the silica nanoparticle bilayer followed by metal deposition.
  • Characterization of SERS performance using 632.8 nm incident light and Rhodamine 6G as a probe molecule.

Main Results:

  • The 3D PLAS exhibits high reproducibility and enormous SERS enhancement.
  • A spatially averaged SERS enhancement factor on the order of 5 × 10^7 was achieved.
  • Local enhancement factors were found to be significantly higher and tunable by optimizing parameters.

Conclusions:

  • The proposed method provides an effective route to fabricate highly ordered, 3D SERS substrates.
  • The 3D PLAS demonstrates excellent potential as a promising SERS substrate for sensitive detection.
  • Optimization of fabrication parameters can further improve the SERS performance.