Pathways to inflammation: acne pathophysiology
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Updated: Jun 1, 2026

A Rat Model of Compound Acne
Published on: November 1, 2024
Marisa Taylor1, Maria Gonzalez, Rebecca Porter
1Department of Dermatology, Cardiff University School of Medicine, UK. TaylorM4@cf.ac.uk
Abstract:
Acne vulgaris affects as much as 80% of the adolescent population and persists in approximately 3% of middle-aged adults. Only a percentage of these persons seek medical help, however, acne can cause levels of anxiety and depression akin to a chronic illness. A recurring question from patients who seek help from various healthcare professionals - their pharmacist, family doctor or dermatologist, is "why?" They also ask questions about a possible familial link, the impact of their diet and the association with their hormones. The following review aims to link these factors with the end result - inflammation.
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