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Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma
Abstract:
Intracranial involvement in multiple myeloma (MM) is rarely found, especially with dural involvement. There are only a few cases found concerning MM with intracranial involvement. MM usually involves an older group of patients. Cases involving young patients are very rare. The differential diagnosis of a dural plasmacytoma includes meningioma, metastasis, lymphoma and sarcoma of the dura mater. We present a young patient, 33 years old, with MM presenting an intracerebral mass mimicking meningioma on MRI. MM was diagnosed the previous year. The patient presented with headache, balance disturbance and back pain. MRI revealed an occipital extra-axial mass with a dural tail. Histopathological examination after excision showed MM. Published literatures on intracranial involvement of MM are also discussed. Plasmacytoma should be considered in the differential diagnosis of a solitary dural mass, particularly in a patient with MM.
Insights
Intracranial involvement in multiple myeloma (MM) is rare, particularly in young adults. This case highlights a dural plasmacytoma mimicking meningioma in a 33-year-old, emphasizing MM in differential diagnoses.
Area of Science:
- Neurology
- Oncology
Background:
- Intracranial involvement in multiple myeloma (MM) is uncommon, with dural involvement being exceptionally rare.
- MM typically affects older individuals; cases in younger patients are exceedingly rare.
Observation:
- A 33-year-old patient with a history of MM presented with headache, balance issues, and back pain.
- MRI revealed an occipital extra-axial mass with a dural tail, initially mimicking a meningioma.
Findings:
- Histopathological examination confirmed the mass to be a manifestation of MM (plasmacytoma).
- This case underscores the importance of considering MM in the differential diagnosis of solitary dural masses.
Implications:
- Highlights the potential for rare intracranial presentations of MM, even in young patients.
- Suggests that plasmacytoma should be included in the differential diagnosis for dural masses, especially in patients with a known MM diagnosis.
