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Related Experiment Video

Updated: Jun 1, 2026

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags

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Published on: January 17, 2019

Controlled fragrant molecule release from surface-tethered cyclodextrin host-guest inclusion complexes.

W C E Schofield¹, J P S Badyal

¹Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, England, United Kingdom.

ACS Applied Materials & Interfaces

|May 27, 2011

Summary

Surface-tethered beta-cyclodextrin enables long-lasting fragrance release through host-guest complexation. This method allows for easy recharging of perfume molecules, offering a sustainable scent delivery system.

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Published on: July 19, 2022

Area of Science:

Materials Science
Supramolecular Chemistry

Background:

Beta-cyclodextrin (β-CD) is a cyclic oligosaccharide known for its ability to form inclusion complexes.
Tethering β-CD to surfaces allows for the development of functional materials with controlled molecular interactions.

Purpose of the Study:

To develop a method for immobilizing β-cyclodextrin onto solid surfaces.
To investigate the use of surface-tethered β-CD for the controlled release of fragrance molecules.
To assess the longevity and rechargeability of the fragrance delivery system.

Main Methods:

Williamson ether synthesis for surface functionalization.
Pulsed plasma deposition of poly(4-vinylbenzyl chloride) as a linker layer.
Infrared spectroscopy and quartz crystal microbalance measurements for monitoring molecular loading and release.

Main Results:

Successful tethering of β-cyclodextrin to solid surfaces was achieved.
Host-guest inclusion complex formation was confirmed for perfume molecules.
Sustained fragrance release over several months was observed.
The system demonstrated easy rechargeability.

Conclusions:

Surface-immobilized β-cyclodextrin is an effective platform for long-term fragrance delivery.
The developed method offers a robust and renewable approach for scent applications.
This technology has potential for use in various consumer products requiring controlled fragrance release.