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A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
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Body-weight-supported treadmill rehabilitation after stroke
Pamela W Duncan1, Katherine J Sullivan, Andrea L Behrman
1Department of Community and Family Medicine, Doctor of Physical Therapy Division, Duke University, Durham, NC 27705, USA. pamela.duke@duke.edu
The New England Journal of Medicine
|May 27, 2011
Summary
Locomotor training after stroke showed no significant benefit over home exercise programs. Early or late treadmill training did not improve functional walking ability compared to supervised home exercises.
Area of Science:
- Neurology
- Physical Therapy
- Rehabilitation Medicine
Background:
- Locomotor training (LT) aids walking recovery post-stroke.
- Its optimal timing and effectiveness remain unclear.
Purpose of the Study:
- To compare early vs. late LT with home exercise for stroke recovery.
- To assess functional walking ability 1 year post-stroke.
Main Methods:
- 408 stroke survivors stratified by walking impairment (moderate/severe).
- Randomized to early LT, late LT, or home exercise program.
- Interventions lasted 12-16 weeks; primary outcome at 1 year.
Main Results:
- 52% improved functional walking ability; no significant difference between LT groups and home exercise.
- Similar improvements in walking speed, motor recovery, balance, and quality of life across groups.
- LT groups reported more dizziness; early LT had more falls in severe impairment cases.
Conclusions:
- Locomotor training was not superior to home exercise for improving functional walking post-stroke.
- Timing of LT initiation did not impact 1-year outcomes.
- Home-based programs offer a comparable alternative to intensive LT.

