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Sweet's syndrome associated with the intake of a selective cyclooxygenase-2 (COX-2) inhibitor
Aristóteles Rosmaninho1, Inês Lobo, Manuela Selores
1Dermatology Department, Centro Hospitalar do Porto, EPE-HSA, Porto, Portugal. arisrosmaninho@gmail.com
Abstract:
Sweet's syndrome (SS; acute febrile neutrophilic dermatosis) is a skin disorder characterized by acute tender erythematous plaques or nodules that may blister and ulcerate. The disease presents in several clinical settings including: classical (idiopathic) SS, malignancy-associated SS and drug-induced SS. Several drugs have been implicated in the etiopathogenesis of the disease with the most frequent being the granulocyte-colony stimulating factor. We report and discuss a case of SS associated with the intake of a selective cyclooxygenase-2 inhibitor, which has been rarely reported.
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