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Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest
Published on: August 6, 2015
Myocardial bridging with a coronary artery aneurysm and left ventricular stunning
Manish Motwani1, Sanjay Arya, John E MacDonald
1Department of Cardiology, Royal Albert Edward Infirmary, Wigan, United Kingdom. mani.motwani@yahoo.com
Insights
This case report details a rare combination of myocardial bridging and coronary artery aneurysm, which led to transient left ventricular dysfunction. It highlights the infrequent occurrence of myocardial stunning in such complex cardiac conditions.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Medical Case Reports
Background:
- Myocardial bridging involves a segment of a coronary artery traversing through heart muscle tissue, potentially leading to ischemia.
- Coronary artery aneurysms are dilations of the coronary arteries, which can increase the risk of thrombosis and rupture.
- Myocardial stunning is a reversible impairment of myocardial contractility following transient ischemia.
Observation:
- The case presents an unusual co-occurrence of myocardial bridging and a coronary artery aneurysm.
- This combination resulted in acute transient left ventricular dysfunction.
- The dysfunction was attributed to myocardial stunning, a rare complication in this context.
Findings:
- Literature search revealed only one prior case of coronary aneurysms associated with myocardial bridging.
- While angina and myocardial infarction are reported with myocardial bridging, myocardial stunning is exceptionally rare.
- This case underscores the potential for myocardial stunning in complex coronary artery anomalies.
Implications:
- This report expands the understanding of rare cardiovascular presentations.
- It emphasizes the need for considering myocardial stunning in patients with combined myocardial bridging and coronary aneurysms.
- Further research into the pathophysiology and management of these rare combined conditions is warranted.
Abstract:
The authors present a case demonstrating the unusual combination of myocardial bridging with a coronary artery aneurysm complicated by acute transient left ventricular dysfunction due to myocardial stunning. The pathophysiology and current insights into myocardial bridging, coronary aneurysms and myocardial stunning are briefly discussed. The literature reveals only one other reported case of coronary aneurysms associated with myocardial bridging. In addition, although there are several reports of angina and myocardial infarction complicating bridging, there is only 1 other report of myocardial stunning specifically.
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