Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Phase Contrast and Differential Interference Contrast Microscopy

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same authorSame journal

Medical physics aspects of cancer care in the Asia Pacific region: 2011 survey results.

Biomedical imaging and intervention journal·2012

Same author

Radiofrequency ablation of a misdiagnosed Brodie's abscess.

Biomedical imaging and intervention journal·2012

Same author

Optimising the scan delay for arterial phase imaging of the liver using the bolus tracking technique.

Biomedical imaging and intervention journal·2012

Same author

The birth of an open access multidisciplinary online journal.

Biomedical imaging and intervention journal·2011

Same author

Improved fracture detection using the mammographic film-screen combination.

Biomedical imaging and intervention journal·2011

Same author

Sustaining and strengthening biij.

Biomedical imaging and intervention journal·2011

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Development of a randomised contrast detail digital phantom for observer detectability study.

Ms Nizam¹, Kh Ng, Bjj Abdullah

¹Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Biomedical Imaging and Intervention Journal

|May 27, 2011

Summary

Optimal viewing conditions, including monitor luminance and ambient illuminance, significantly improve the detectability of lesions in radiological images. This study highlights the importance of controlled environments for accurate medical diagnoses.

Keywords:

Image quality contrast detail perception receiver operating characteristics

More Related Videos

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

Published on: July 14, 2020

Related Experiment Videos

Last Updated: Jun 1, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

Published on: July 14, 2020

Area of Science:

Medical Imaging
Radiology
Human Perception

Background:

Radiological diagnosis accuracy relies heavily on image display conditions.
Key factors influencing image quality include display luminance and ambient room illumination.

Purpose of the Study:

To investigate the relationship between lesion detectability and monitor luminance.
To determine the impact of ambient illuminance on diagnostic performance.

Main Methods:

A perceptual study was conducted using a custom-designed statistical test pattern.
The test pattern simulated digital lesions with varying sizes and contrasts.
Receiver Operating Characteristic (ROC) analysis was employed to evaluate detectability.

Main Results:

Optimal viewing conditions were identified, significantly enhancing lesion detection.
Both monitor luminance and ambient illuminance were found to affect performance.

Conclusions:

Establishing optimal viewing conditions is crucial for improving radiological diagnostic accuracy.
Adjusting display and ambient lighting can significantly boost the efficacy of medical image interpretation.