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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

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Published on: February 6, 2019

Dose optimisation during imaging in radiotherapy.

¹Christian Medical College, Vellore, India.

Biomedical Imaging and Intervention Journal

|May 27, 2011

Summary

This summary is machine-generated.

Advanced imaging in radiotherapy, including amorphous silicon (a-Si) electronic portal imaging and cone beam CT, delivers small doses to normal tissues. These doses, though minimal, may increase the risk of secondary cancers and warrant optimization.

Keywords:

Animal irradiator radiation beam measurement radiobiology rodent irradiation

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

Medical Physics
Radiation Oncology
Radiotherapy Imaging

Background:

Advanced imaging techniques like amorphous silicon (a-Si)-based electronic portal imaging and cone beam CT are crucial for precise radiotherapy delivery.
These systems visualize target organs and ensure accurate patient setup and treatment delivery before radiation administration.
The radiation dose absorbed by adjacent normal tissues during these imaging procedures has received limited attention.

Purpose of the Study:

To review existing research on radiation doses to normal tissues during radiotherapy imaging procedures.
To discuss methods for optimizing these imaging doses to minimize potential risks.
To address the concern of stochastic effects, particularly secondary malignancy induction, from these low-dose exposures.

Main Methods:

Review of published literature on radiation dosimetry for radiotherapy imaging systems.
Analysis of doses delivered by amorphous silicon (a-Si)-based electronic portal imaging.
Evaluation of doses from kV and MV cone beam CT imaging protocols.

Main Results:

Imaging procedures in radiotherapy deliver small doses to adjacent normal tissues.
While significantly lower than therapeutic doses, these imaging doses are a concern for stochastic effects.
The potential for increased risk of secondary malignancy induction cannot be disregarded.

Conclusions:

The cumulative dose to normal tissues from repeated radiotherapy imaging warrants careful consideration.
Further research and optimization of imaging techniques are necessary to minimize radiation exposure.
Strategies to reduce dose during imaging are essential for improving the overall safety profile of radiotherapy.