Related Experiment Video
Updated: Jun 1, 2026
Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Advances in non-surgical treatments for urinary tract infections in children
Stephen Shei-Dei Yang1, I-Ni Chiang, Chia-Da Lin
1Division of Urology, Buddhist Tzu Chi General Hospital, Taipei Branch, No. 289 Chienkuo Road, Xindian City, Taipei, 231, Taiwan.
Insights
Non-surgical approaches are crucial for pediatric urinary tract infections (UTI) due to antibiotic resistance. These methods include behavioral changes, topical steroids, supplements, and catheterization, offering safer alternatives.
Area of Science:
- Pediatric Urology
- Infectious Diseases
- Non-surgical Interventions
Background:
- Antibiotic resistance is increasing the need for alternative pediatric UTI treatments.
- Non-surgical management offers a less invasive approach with fewer side effects for children.
Purpose of the Study:
- To review and summarize non-surgical management strategies for pediatric urinary tract infections (UTI).
- To identify various non-invasive therapeutic options beyond antibiotics and surgery.
Main Methods:
- A comprehensive literature search was conducted on PubMed.
- Keywords included various non-surgical treatments and pediatric UTI.
- Studies focusing on management other than surgical correction and antibiotics were selected.
Main Results:
- Non-surgical options for pediatric UTI include behavioral modification, topical steroids for phimosis, nutritional supplements (breast milk, cranberry, probiotics, vitamin A), biofeedback, anticholinergics, alpha-blockers, and intermittent catheterization.
- These methods address issues like dysfunctional voiding, phimosis, and large post-void residual volumes.
Conclusions:
- Published studies often have small sample sizes and lack randomization.
- Further high-quality research is needed to validate these non-operative management strategies for pediatric UTI.
Objective:
With growing antibiotics failure due to emerging resistance of bacteria, non-surgical management of pediatric UTI plays a more important role because of its non-invasive characteristics and little adverse effects.
Methods:
We searched the Pubmed for management of UTI in children other than surgical correction and antibiotics using terms: risk factor, prepuce/phimosis, steroid cream/steroid, behavioral therapy, urotherapy, biofeedback/pelvic floor exercise, adrenergic antagonist, anticholinergics, diet/dietary, dysfunctional voiding/dysfunctional elimination syndrome, constipation, dietary, clean intermittent catheterization, probiotics/lactobacillus, cranberry, vitamin supplement, breastfeeding, breast milk, with infant/child/children/pediatrics/pediatrics and urinary tract infection.
Results:
The proposed non-surgical management of pediatric UTI included behavioral modification (timed voiding and adequate fluids intake), topical steroid for phimosis, nutrient supplements (breast milk, cranberry, probiotics, and vitamin A), biofeedback training for dysfunctional voiding, anticholinergics for reducing intravesical pressure, alpha-blockers in dysfunctional voiding and neurogenic bladder, and intermittent catheterization for children with large PVR.
Conclusion:
The published reports usually included small number of patients and were lacking of randomization and controlled group. Further well-designed studies are warranted to support the concepts of non-operative management for pediatric UTI.
Related Concept Videos
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
01:17Urinary Tract Infection IV: Nursing Management
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
01:26Urine Studies II: Urine Culture and Sensitivity Test
01:30Urinary Tract Calculi III: Medical Management
01:25Urinary Tract Calculi VI: Surgical Management