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Ovarian carcinoma presenting with axillary lymph node metastasis: a case report
F Ceccarelli1, S Barberi, A Pontesilli
1Department of Surgery "P. Valdoni", Sapienza University of Rome, Rome, Italy. fra.ceccarelli@virgilio.it
European Journal of Gynaecological Oncology
|May 28, 2011
Summary
This case study highlights a rare instance of ovarian cancer metastasizing to the axilla as the initial presentation. Diagnostic cytology and histology were crucial in identifying the extrabdominal metastasis and guiding treatment.
Area of Science:
- Oncology
- Pathology
Background:
- Ovarian cancer typically remains confined to the abdomen.
- Extrabdominal metastases are uncommon at initial presentation.
Observation:
- A 48-year-old woman presented with an isolated axillary mass.
- Cytological and histological examination of the axillary lymph nodes revealed psammoma bodies and tumor markers (OC-125, WT1).
Findings:
- The axillary mass was diagnosed as metastatic adenocarcinoma from ovarian origin.
- Imaging confirmed a right ovarian mass, and elevated CA125 levels were detected.
- Histopathology confirmed poorly differentiated serous-papillary ovarian carcinoma.
Implications:
- Atypical extrabdominal presentations of ovarian cancer can occur.
- Cytological and histological analyses are vital for diagnosing metastatic adenocarcinoma with unusual clinical signs.
- Early identification of metastatic spread is critical for effective patient management.
