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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Environmental risk factors in pediatric psoriasis: a multicenter case-control study
Müge G Ozden1, Nilgün S Tekin, Mehmet A Gürer
1Dermatology Department, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey. mgulerozden@hotmail.com
Pediatric Dermatology
|May 28, 2011
Summary
Environmental tobacco smoke exposure, stressful life events, and high body mass index (BMI) are linked to childhood-onset psoriasis. These factors may influence the development of pediatric psoriasis in children.
Area of Science:
- Dermatology
- Pediatrics
- Epidemiology
Background:
- Childhood-onset psoriasis is a chronic inflammatory skin condition.
- Identifying risk factors for pediatric psoriasis is crucial for early intervention.
Purpose of the Study:
- To investigate potential risk factors, including breastfeeding, associated with the development of childhood-onset psoriasis.
- To analyze the influence of environmental factors and lifestyle on pediatric psoriasis incidence.
Main Methods:
- A multicenter case-control study with prospective data collection was conducted.
- Data on family history, environmental exposures, BMI, breastfeeding, and life events were collected from 537 pediatric psoriasis patients and 511 controls.
- Standardized questionnaires were utilized for data acquisition.
Main Results:
- Children with psoriasis showed higher exposure to environmental tobacco smoke at home and experienced more stressful life events.
- Increased odds ratios (OR) were observed for smoking (2.90) and stressful life events (2.94).
- Higher body mass index (BMI > 26) was also associated with pediatric psoriasis (OR=2.52).
Conclusions:
- Environmental tobacco smoke exposure, stressful life events, and high BMI are significant risk factors for childhood-onset psoriasis.
- These factors may play a role in the pathogenesis of pediatric psoriasis.
- Breastfeeding, cow's milk intake, and delivery method were not significantly associated with pediatric psoriasis in this study.
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