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Updated: Jun 1, 2026

Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Vascular endothelial growth factor expression up-regulated by endometrial ischemia in secretory phase plays an
Qiong-zhen Ren1, Zhi-hong Qian, Su-hong Jia
1Department of Obstetrics and Gynecology, Second Hospital Affiliated with Soochow University, Suzhou City, Jiangsu, People's Republic of China.
Abstract:
Primary human endometrial cells were exposed to hypoxia preconditioning (HPC), HPC-hypoxia, and hypoxia conditions, and then endometrial tissue treated with ischemia preconditioning (IPC) was transplanted onto the chick embryo chorioallantoic membrane to investigate the role of slight ischemia of endometrium in the pathologic process of endometriosis. IPC up-regulated vascular endothelial growth factor expression and decreased apoptosis of endometrial cells, thus facilitating the endometrial fragments' ectopic implantation.
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