Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of keratometry using SS-OCT and dual Scheimpflug-Placido imaging in postmyopic corneal refractive surgery eyes.

Journal of cataract and refractive surgery·2022
Same author

Comment on: Tape Splint Tarsorrhaphy for Persistent Corneal Epithelial Defects.

American journal of ophthalmology·2022
Same author

Comparison of Simulated and True Keratometry Measurements Using Swept-Source Optical Coherence Tomography and Dual Scheimpflug-Placido Imaging.

Journal of ophthalmology·2021
Same author

Orbital Compartment Syndrome After High-speed Air-Gasoline Blast Injury.

Ophthalmic plastic and reconstructive surgery·2020
Same author

Twist and out intraocular lens removal.

Journal of cataract and refractive surgery·2020
Same author

Monocular Clinical Outcomes and Range of Near Vision following Cataract Surgery with Implantation of an Extended Depth of Focus Intraocular Lens.

Journal of ophthalmology·2019

Related Experiment Video

Updated: Jun 1, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Brevundimonas diminuta keratitis.

Rahul T Pandit1

  • 1Methodist Eye Associates, Department of Ophthalmology, The Methodist Hospital, Houston, TX 77030, USA. rtpandit@tmhs.org

Eye & Contact Lens
|May 28, 2011
PubMed
Summary

This case report details the first documented instance of keratitis caused by Brevundimonas diminuta, a rare gram-negative bacillus. It highlights the importance of identifying secondary infections in compromised corneas.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Corneal ulcers are serious ocular infections often caused by bacteria.
  • Contact lens wear is a significant risk factor for microbial keratitis.

Observation:

  • A 66-year-old soft contact lens wearer presented with a large Pseudomonas aeruginosa corneal ulcer.
  • Following initial treatment, the patient developed a secondary keratitis.
  • Repeat cultures identified Brevundimonas diminuta as the causative agent of the secondary infection.

Findings:

  • Targeted antibiotic therapy, adjusted based on bacterial sensitivities, led to slow but complete resolution of the corneal ulcer.
  • The patient's visual acuity improved from Hand Motions to 20/40.
  • A minimal corneal scar was the only residual finding.

More Related Videos

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
05:05

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

Related Experiment Videos

Last Updated: Jun 1, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
05:05

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

Implications:

  • This is the first reported case of ocular infection with Brevundimonas diminuta.
  • Clinicians must consider rare secondary pathogens in non-resolving keratitis.
  • Pharmacotherapy adjustments guided by serial cultures and sensitivity testing are crucial for managing complex corneal infections.