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Updated: Jun 1, 2026
14:06
Isolation of Precursor B-cell Subsets from Umbilical Cord Blood
Published on: April 16, 2013
Umbilical cord blood banking: an update
Merlin G Butler1, Jay E Menitove
1Departments of Psychiatry & Behavioral Sciences and Pediatrics, Kansas University Medical Center, Kansas City, KS 66160, USA. mbutler4@kumc.edu
Journal of Assisted Reproduction and Genetics
|May 28, 2011
Summary
Umbilical cord blood offers a rich source of stem cells for treating various diseases. Banking options include private and public, with ongoing research into new therapeutic applications beyond blood disorders.
Area of Science:
- Hematology
- Regenerative Medicine
- Transplantation Immunology
Background:
- Umbilical cord blood (UCB) is a rich source of hematopoietic stem and progenitor cells.
- UCB transplantation is an established alternative to bone marrow transplantation.
- UCB therapies are used for hematological disorders, immunological defects, and genetic diseases.
Purpose of the Study:
- To review the current status of umbilical cord blood banking.
- To summarize the history and applications of UCB banking.
- To explore the potential of UCB in treating non-hematological diseases.
Main Methods:
- Literature review of UCB banking and transplantation.
- Analysis of UCB storage options (private vs. public).
- Summary of current and emerging UCB therapeutic uses.
Main Results:
- Over 25,000 allogeneic UCB transplantations have been performed globally.
- More than 780,000 units are stored in private banks and over 400,000 in public banks.
- Research is expanding UCB applications to conditions like heart disease, stroke, and cancer.
Conclusions:
- UCB banking provides critical stem cell resources for transplantation.
- Both private and public banking models serve distinct purposes.
- Emerging research highlights UCB's potential in treating a wider range of diseases.
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