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Related Experiment Video

Updated: Jun 1, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Controversies around carotid stenting.

I Q Grunwald¹, A L Kühn

¹Acute Vascular Imaging Centre, NIHR Oxford Biomedical Research Centre, University of Oxford, John Radcliffe Hospital, Oxford, UK. i.grunwald@web.de

Acta Chirurgica Belgica

|May 31, 2011

Summary

Carotid artery stenting (CAS) is a newer alternative to surgery for carotid artery stenosis. This review critically examines randomized trials comparing CAS to carotid endarterectomy (CEA), focusing on stroke prevention efficacy and safety.

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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

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Last Updated: Jun 1, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Area of Science:

Vascular Surgery
Neurology
Interventional Cardiology

Background:

Carotid artery stenosis (CAS) is a significant risk factor for ischemic stroke.
Carotid endarterectomy (CEA) has been the gold standard surgical treatment.
Carotid artery stenting (CAS) emerged as a less invasive endovascular alternative.

Purpose of the Study:

To critically review and compare the efficacy and safety of CAS versus CEA for stroke prevention.
To address controversial trial requirements and questionable conclusions in previous studies.
To evaluate the established therapy (CEA) against the newer endovascular technique (CAS).

Main Methods:

Systematic review of randomized controlled trials (RCTs).
Critical analysis of study designs, patient populations, and endovascular approach requirements.
Meta-analysis of efficacy (stroke prevention) and safety (adverse events) outcomes.

Main Results:

Previous trials comparing CAS and CEA had methodological limitations.
Controversial endovascular approach requirements in some trials led to questionable efficacy conclusions.
Safety profiles of CAS and CEA require careful consideration in specific patient subgroups.

Conclusions:

The optimal treatment strategy for carotid artery stenosis remains debated.
Further high-quality RCTs with standardized endovascular protocols are needed.
Patient selection and risk stratification are crucial for determining the best intervention for stroke prevention.