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In vivo detection of injected free radicals by Overhauser effect imaging
1Institut de Physique Biologique, UA du CNRS 1173, Faculté de Medecine, Université Louis Pasteur, Strasbourg, France.
Magnetic Resonance in Medicine
|April 1, 1990
Abstract:
Proton dynamical polarization is a method which unites the advantages of continuous wave ESR sensitivity and pulsed NMR imaging in order to localize free radicals. Injected nitroxide has been imaged for the first time in living rats. The high sensitivity of this method to oxygen is demonstrated.