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Related Experiment Video

Updated: Jun 1, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Multiple thymic carcinoids.

Koji Kawaguchi¹, Noriyasu Usami, Toshiki Okasaka

¹Division of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. gucci@med.nagoya-u.ac.jp

The Annals of Thoracic Surgery

|May 31, 2011

Summary

This summary is machine-generated.

This rare case highlights simultaneous thymic carcinoids, with one tumor spontaneously regressing. Total thymectomy is suggested for treating thymic carcinoid due to potential multicentric origins.

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Area of Science:

Oncology
Thoracic Surgery
Pathology

Background:

Thymic carcinoids are rare neuroendocrine tumors originating in the thymus.
Multiple thymic carcinoids are exceptionally uncommon, posing diagnostic and therapeutic challenges.

Observation:

A 68-year-old male presented with two similarly sized anterior mediastinal masses detected via chest CT.
One mass exhibited spontaneous regression, decreasing from 25 mm to 16 mm in diameter.
Pathological examination confirmed both masses as atypical carcinoids following total thymectomy.

Findings:

The case documents a rare instance of simultaneous, bilateral thymic carcinoids.
One of the thymic carcinoid tumors demonstrated significant spontaneous regression.
Histopathology confirmed both lesions as atypical carcinoid tumors.

Implications:

This case underscores the possibility of multicentric origins for thymic carcinoids.
It supports total thymectomy as the optimal surgical approach for thymic carcinoid management.
Further research into the behavior and origins of multiple thymic carcinoids is warranted.