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Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
[Prolonged stay in pediatric intensive care units: mortality and healthcare resource consumption]
R González-Cortés1, J López-Herce-Cid, A García-Figueruelo
1Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España.
Insights
Patients with prolonged stays in pediatric intensive care units (PICUs) face significantly higher mortality and resource use. Early identification of at-risk children is crucial for improving outcomes and resource allocation.
Area of Science:
- Pediatric Critical Care Medicine
- Intensive Care Unit Management
- Healthcare Resource Utilization
Background:
- Prolonged stays in Pediatric Intensive Care Units (PICUs) represent a significant challenge in critical care.
- Understanding the outcomes and resource demands of these patients is essential for optimizing care.
Purpose of the Study:
- To analyze mortality rates and healthcare resource consumption in pediatric patients with prolonged PICU stays.
- To identify characteristics associated with prolonged PICU stays.
Main Methods:
- Retrospective, descriptive case series study conducted in a medical-surgical PICU.
- Analysis of data from 2118 patients between 2006 and 2010, focusing on 83 patients with stays of 28 days or more.
Main Results:
- Patients with prolonged PICU stays exhibited a substantially higher mortality rate (22.9%) compared to other patients (2%).
- High incidence of nosocomial infections (96.3%) and extensive use of healthcare resources, including mechanical ventilation, blood products, vasoactive drugs, and ECMO, were observed.
- A significant proportion of deaths in this group occurred after treatment withdrawal or cessation of resuscitation efforts.
Conclusions:
- Critical children with prolonged PICU stays experience significant morbidity, mortality, and consume substantial healthcare resources.
- There is a need for early identification strategies for patients at risk of prolonged stays to tailor therapeutic measures and improve treatment efficiency.
Objective:
To analyze mortality and resource consumption in patients with long stays in pediatric intensive care units (PICUs).
Design:
A retrospective, descriptive case series study.
Scope:
Medical-surgical PICU in a third level hospital.
Patients:
Data were collected from patients with a stay of 28 days or more in PICU between 2006 and 2010. Of the 2118 patients assisted in this period, 83 (3.9%) required prolonged stay.
Study Variables:
Morbidity-mortality and resource consumption among patients with prolonged stay in the PICU.
Results:
Mortality was higher in patients with a long stay (22.9%) than in the rest of patients (2%) (p<0.001). In 52.6% of these patients, death occurred after withdrawal of treatment or after not starting resuscitation measures. Patients with prolonged stay showed a high incidence of nosocomial infection (96.3%) and an important consumption of healthcare resources (97.6% required conventional mechanical ventilation, 90.2% required transfusion of blood products, 86.7% required intravenous vasoactive drugs and 22.9% required extracorporeal membrane oxygenation [ECMO]).
Conclusions:
Critical children with prolonged stay in the PICU show important morbidity and mortality, and an important consumption of healthcare resources. The adoption of specific measures permitting early identification of patients at risk of prolonged stay is needed in order to adapt therapeutic measures and available resources, and to improve treatment efficiency.
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