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Abdominal aortic aneurysm repair complicated by infection with Clostridium septicum
Sarah E Colwick1, Fuad Alkhoury, Jeremiah T Martin
1Department of Surgery, Hospital of Saint Raphael, New Haven, CT 06511, USA. scolwick@gmail.com
Abstract:
Aortic stent-graft infection after endovascular abdominal aortic aneurysm (AAA) repair is an uncommon, but very serious complication with potentially devastating consequences.(1) Traditional open techniques of repair of AAA demonstrate an infection rate of 0.5-3%. The exact rate of infection with endovascular repair is unknown, but literature review demonstrates an overall incidence of 0.43-1.17% retrospectively.(2,3) Etiology of endovascular graft infections typically results from flora derived from the skin or gastrointestinal tract.(4)Clostridium septicum is a naturally occurring anaerobic bacterium native to the gastrointestinal tract. It is typically associated with spontaneous nontraumatic gas gangrene owing to bacteremia from the gastrointestinal tract with an incidence rate of 0.07%.(5) To our knowledge, this is the first reported case of endovascular AAA graft infection owing to Clostridium septicum species.
Insights
Endovascular abdominal aortic aneurysm repair can lead to rare but serious stent-graft infections. This case highlights Clostridium septicum as a potential, previously unreported cause of such infections.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Microbiology
Background:
- Endovascular Abdominal Aortic Aneurysm (AAA) repair is a common procedure.
- Aortic stent-graft infection is a rare but severe complication.
- Infections typically arise from skin or gastrointestinal flora.
Observation:
- Clostridium septicum, an anaerobic bacterium from the GI tract, causes spontaneous gas gangrene.
- This is the first reported instance of Clostridium septicum causing an endovascular AAA graft infection.
Findings:
- The patient developed an endovascular AAA graft infection.
- The causative agent was identified as Clostridium septicum.
Implications:
- This finding expands the known pathogens responsible for endovascular graft infections.
- Awareness of Clostridium septicum is crucial for diagnosing and treating rare AAA graft infections.
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