[How to write an original article for a biomedical journal]

Writing a scientific article is difficult, but skillful writing does not depend only on talent. This skill can be learned, and writing requires discipline and dedication. This article discusses the basic characteristics of the IMRaD (Introduction, Material and methods, Results, and Discussion) format and the contents of each section, as well as the characteristics of the title, abstract, and bibliographical references. It also provides a list of five characteristics that are essential for an original article published in a scientific journal: objective, permission of the ethics committee, a structured material and methods section, results that follow appropriately from the material and methods section, and a structured discussion. Furthermore, we provide a basic outline for the discussion section consisting of stating the most important results, developing a critical discussion of the results, stating and discussing the strengths and limitations of the study, and elaborating the final synthesis.