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Updated: Jun 1, 2026

MicroRNA Detection in Prostate Tumors by Quantitative Real-time PCR (qPCR)
Published on: May 16, 2012
TRP channels in prostate cancer: the good, the bad and the ugly?
Dimitra Gkika1, Natalia Prevarskaya
1Inserm U1003, Equipe labellisée par la Ligue Nationale contre le cancer, Villeneuve d'Ascq, France. dimitra.gkika@univ-lille1.fr
Abstract:
During the last decade, transient receptor potential (TRP) channels emerge as key proteins in central mechanisms of the carcinogenesis such as cell proliferation, apoptosis and migration. Initial studies showed that expression profile of some TRP channels, notably TRP melastatin 8 (TRPM8), TRP vanilloid 6 (TRPV6),TRP canonical (TRPC6) and TRPV2, is changing during the development and the progression of prostate cancer towards the hormone-refractory stages. The link between the change in expression levels and the functional role of these channels in prostate cancer is step by step being elucidated. These recent advances are here described and discussed.
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