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Anticomplement activity of isolated compounds from Artemisia montana
Hyung-In Moon1, Seil Jung, Young-Choon Lee
1Department of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South Korea. himun68@dau.ac.kr
Abstract:
The study evaluated the anticomplement activity from isolated compounds from Artemisia montana (Nakai) Pamp. from South Korea on the classical pathway. In a previous work, A. montana (Nakai) Pamp. chloroform extracts showed inhibitory activity against complement system. The chromatographic separation of a chloroform chloride extract of A. montana (Nakai) Pamp. led to the isolation of four compounds. Their structures were characterized to be ezoartemin, yamayomoginin, ezomontanin and 11,13-dihydroezomontanin by spectroscopic data. This is the first report of anticomplement activity of isolated compounds from A. montana (Nakai) Pamp.
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