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AICDA expression in BCR/ABL1-positive acute lymphoblastic leukaemia is associated with a peculiar gene expression

Monica Messina1, Sabina Chiaretti, Ilaria Iacobucci

  • 1Division of Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University of Rome, Rome.

British Journal of Haematology
|June 1, 2011
PubMed

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Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...