[The relationship between obesity and microalbuminuria among general population in Beijing area]

To investigate the correlation between microalbuminuria (MAU) and obesity and its indexes, including BMI, waist circumference (WC), and waist-to-hip ratio (WHR), among partial community population in Beijing.

A total of 2080 subjects who took physical examination in Beijing, including 810 men and 1270 women with a mean age of (50.9 ± 13.1) years, were enrolled. The informed consent has been achieved from each patients. BMI and WHR were calculated based on collected data of height, weight, WC, and hipline. Urine albumin-creatinine ratio (ACR) within the range of 30 - 300 mg/g was classified as MAU. The subjects were divided into normal albuminuria (NAU) group and MAU group. The correlations between MAU and different obesity indexes including BMI, WC and WHR, were analyzed.

Among the 2080 subjects, there was a positive correlation between BMI (r = 0.1276, P < 0.01) and ACR, and WC (r = 0.0840, P < 0.01) and ACR. WHR and ACR was irrelevant (P > 0.05). In univariate analysis, there was significant difference in BMI ≥ 28 kg/m(2) (OR = 2.02) and WC ≥ 85 cm (male) or ≥ 80 cm (female) (OR = 1.69) between NAU group and MAU group (P < 0.05). There was no significant difference in BMI 24- < 28 kg/m(2), and WHR ≥ 0.90 (male) or ≥ 0.85 (female) between NAU group and MAU group (P ≥ 0.05). Multivariate logistic regression analysis revealed that BMI (OR = 1.06) was an isolated independent risk factor of MAU from age (OR = 1.01), female (OR = 1.42), systolic blood pressure (OR = 1.01), TC (OR = 1.93) and HDL-C (OR = 0.54).

Obesity is an independent risk factor of MAU among partial community population in Beijing. The correlation between different obesity indexes and MAU also differs.