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Cost-effectiveness of rotavirus vaccination in Bolivia from the state perspective

Emily R Smith1, Emily E Rowlinson, Volga Iniguez

  • 1Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, United States.

Vaccine
|June 1, 2011
PubMed

Insights

Rotavirus vaccination in Bolivia significantly reduces child deaths and healthcare costs. The rotavirus vaccine is cost-effective, offering substantial savings for the Bolivian state.

Area of Science:

  • Public Health
  • Health Economics
  • Vaccinology

Background:

  • Under-five mortality in Bolivia is high, with diarrhea causing 15% of deaths.
  • Rotavirus illness (RI) accounts for 40% of pediatric diarrhea hospitalizations.
  • Rotavirus vaccination (RV) is crucial for reducing morbidity, mortality, and economic burden.

Purpose of the Study:

  • Estimate the economic burden of rotavirus illness in Bolivia.
  • Assess the cost-effectiveness of the rotavirus vaccination program.

Main Methods:

  • Utilized medical records from 287 inpatients and 6751 outpatients for cost assessment.
  • Estimated RI prevalence using 4 years of national hospital surveillance data.
  • Employed a decision-analytic model to evaluate universal RV cost-effectiveness.

Main Results:

  • RI incurs over US$3 million in direct medical costs per 5-year birth cohort.
  • RV reduces outpatient visits, hospitalizations, and deaths by at least 60%.
  • RV is cost-saving at <$3.81/dose and cost-effective at <$194.10/dose.

Conclusions:

  • Rotavirus vaccination is a cost-effective strategy for Bolivia.
  • Data will inform Bolivia's RV program financing decisions amidst changing international subsidies.
Abstract

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