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Updated: Jun 1, 2026

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
05:01

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

Published on: July 1, 2020

GLAMM: Genome-Linked Application for Metabolic Maps

John T Bates1, Dylan Chivian, Adam P Arkin

  • 1Technologies Division, DOE Joint BioEnergy Institute, Emeryville, CA 94608, USA.

Nucleic Acids Research
|June 1, 2011
PubMed

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...