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Event-related distress in kidney disease patients
Sarah Ramer1, Anne Germain, Sheena Dohar
1Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ramer.sarah@medstudent.pitt.edu
Insights
Stressful life events cause significant distress in chronic kidney disease (CKD) patients. High distress correlates with depression and symptom burden, necessitating clinical attention for optimal CKD care.
Area of Science:
- Nephrology
- Psychosomatic Medicine
- Clinical Psychology
Background:
- Chronic kidney disease (CKD) and Stage 5 CKD (CKD5) impose substantial physical and psychosocial burdens.
- The impact of stressful life events on CKD and CKD5 patients remains under-explored.
Purpose of the Study:
- To determine the prevalence of stressful life events in CKD and CKD5 patients.
- To identify factors associated with high levels of event-related distress in these populations.
Main Methods:
- A cross-sectional study involving 181 patients (91 non-dialysis CKD Stages 4-5, 90 CKD5).
- Utilized the Impact of Event Scale (IES) for distress assessment.
- Incorporated Medical Outcomes Study Short Form-36, Patient Health Questionnaire-9 (PHQ-9), and Dialysis Symptom Index (DSI) for comprehensive evaluation.
Main Results:
- 103 subjects reported stressors; 49.5% related to personal health.
- Significant differences observed in age, PHQ-9, and DSI scores between distress groups.
- PHQ-9 scores (OR 1.20) and DSI scores (OR 1.04) independently predicted high event-related distress.
Conclusions:
- Event-related distress is prevalent among CKD and CKD5 patients.
- High distress is linked to increased depressive symptoms and somatic/emotional burden.
- Renal practitioners should consider addressing event-related distress for comprehensive patient care.
Background:
Non-dialysis-dependent chronic kidney disease (CKD) and dialysis-dependent Stage 5 CKD (CKD5) are associated with a significant physical and psychosocial burden. Little is known, however, about the impact of stressful life events on CKD and CKD5 patients. This study aimed to determine the prevalence of stressful life events in CKD and CKD5 patients and identify the factors correlated with high levels of event-related distress.
Methods:
This cross-sectional study's sample consisted of 181 patients (91 with non-dialysis-dependent CKD Stages 4 and 5, 90 with CKD5) who filled out the Impact of Event Scale (IES), which measures subjective distress related to stressful life events. Other measures included scores from the Medical Outcomes Study Short Form-36, Patient Health Questionnaire-9 (PHQ-9) and Dialysis Symptom Index (DSI).
Results:
One hundred and three subjects reported stressors on the IES. Almost half the stressors (49.5%) related to personal health; the rest fell into other categories. There were significant differences between the no stressor, low event-related distress and high event-related distress groups in age (P < 0.001), PHQ-9 score (P < 0.001) and DSI score (P = 0.002). After adjustment, PHQ-9 score was associated with high event-related distress [odds ratio (OR) 1.20, 95% confidence interval (CI) 1.10-1.32], as was DSI score (OR 1.04, 95% CI 1.02-1.07) in a separate model.
Conclusions:
Event-related distress is common in CKD and CKD5 patients. High event-related distress is associated with worse depressive symptoms and greater somatic and emotional symptom burden, even with adjustments for age and gender. The renal practitioner may need to address patients' event-related distress in order to provide optimal care.
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