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Too many mouldy joints - marijuana and chronic pulmonary aspergillosis

Yousef Gargani1, Paul Bishop, David W Denning

  • 1The National Aspergillosis Centre, University Hospital of South Manchester, The University of Manchester, Manchester Academic Health Science Centre, and School of Medicine. Manchester, United Kingdom.

Mediterranean Journal of Hematology and Infectious Diseases
|June 1, 2011
PubMed

Insights

Chronic pulmonary aspergillosis, a lung disease, may be linked to long-term marijuana smoking. This report details two cases and reviews related literature on invasive and allergic aspergillosis.

Area of Science:

  • Pulmonology
  • Mycology
  • Infectious Diseases

Background:

  • Chronic pulmonary aspergillosis (CPA) is a severe lung condition often associated with other pulmonary diseases.
  • Aspergillosis encompasses invasive, allergic, and chronic forms, caused by Aspergillus species.

Purpose of the Study:

  • To investigate the potential association between chronic pulmonary aspergillosis and long-term marijuana smoking.
  • To review existing literature on invasive and allergic aspergillosis in the context of CPA.

Main Methods:

  • Case report of two patients with CPA and a history of long-term marijuana smoking.
  • Literature review of studies on invasive and allergic aspergillosis.

Main Results:

  • Two cases suggest a possible link between chronic pulmonary aspergillosis and prolonged marijuana use.
  • Literature review highlights various presentations and risk factors for aspergillosis.

Conclusions:

  • Long-term marijuana smoking may be a contributing factor or an unrecognized association in chronic pulmonary aspergillosis.
  • Further research is warranted to explore the relationship between marijuana use and aspergillosis development.

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