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Alpha-2 adrenergic receptor function in post-stroke depression
1Department of Psychiatry, Trinity College Medical School, St James's Hospital, Dublin, Ireland.
Psychological Medicine
|May 1, 1990
Abstract:
The growth hormone (GH) response to desipramine was measured in ten patients meeting criteria for post-stroke depression (PSD), eight age-matched post-stroke (PS) non-depressed patients and eight healthy controls. Responses were significantly blunted in patients with PSD. These findings suggest diminished alpha-2 adrenoceptor function may be an important marker for PSD.