Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Primary Lymphoid Organs

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Low-Dose Vemurafenib Plus Rituximab in Front-Line and Relapsed or Refractory Hairy Cell Leukemia: The Scripps Regimen.

Blood advances·2026

Same author

A novel JAK1 variant in chronic eosinophilic leukaemia with response to benralizumab.

British journal of haematology·2026

Same author

Glucagon Like Peptide 1 Receptor Agonists and Age-Related Macular Degeneration Incidence.

Ophthalmology. Retina·2026

Same author

Characterization of Pentosan Polysulfate Sodium Maculopathy With Fluorescence Lifetime Imaging.

Retina (Philadelphia, Pa.)·2026

Same author

Updated consensus guidelines for the diagnosis and management of patients with HCL and HCL variant.

Blood·2026

Same author

Artificial intelligence based assessment of treatment response in wet age related macular degeneration using paired OCT angiography.

Scientific reports·2026

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Published on: January 12, 2024

Primary intraocular lymphoma: a review.

Gregory S Vosganian¹, Saskia Boisot, Kathrin I Hartmann

¹Division of Hematology/Oncology, Scripps Clinic, 10666 N. Torrey Pines Road, La Jolla, CA 92037, USA. vosganian.gregory@scrippshealth.org

Journal of Neuro-Oncology

|June 1, 2011

Summary

Primary intraocular lymphoma (PIOL) is a rare cancer. This case study details a patient with bilateral PIOL who achieved remission but later experienced brain recurrence, highlighting treatment challenges.

More Related Videos

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine

Published on: June 24, 2019

Intravitreous Injection for Establishing Ocular Diseases Model

Intravitreous Injection for Establishing Ocular Diseases Model

Published on: October 1, 2007

Related Experiment Videos

Last Updated: Jun 1, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Published on: January 12, 2024

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine

Published on: June 24, 2019

Intravitreous Injection for Establishing Ocular Diseases Model

Intravitreous Injection for Establishing Ocular Diseases Model

Published on: October 1, 2007

Area of Science:

Ophthalmology
Hematology
Oncology

Background:

Primary intraocular lymphoma (PIOL) is a rare non-Hodgkin lymphoma, often classified as a subtype of primary central nervous system lymphoma.
Understanding PIOL's unique presentation and behavior is crucial for timely diagnosis and effective management.

Observation:

A 65-year-old immunocompetent woman was diagnosed with bilateral PIOL without evidence of systemic disease.
The patient achieved a 16-month remission following initial treatment.

Findings:

Despite initial remission, the patient experienced a recurrence of PIOL in the brain.
This case underscores the potential for PIOL to spread intracranially, even after apparent systemic control.

Implications:

Current diagnostic criteria and treatment strategies for PIOL in immunocompetent patients require careful consideration.
Further research into optimal therapeutic approaches is needed to improve long-term outcomes and prevent central nervous system relapse.