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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

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Published on: December 18, 2012

Herpes zoster optic neuritis.

Breno de Mello Vitor¹, Emílio Castelar Macedo Foureaux, Fernanda Belga Ottoni Porto

¹Centro Oftalmológico de Minas Gerais, Rua Santa Catarina 941, Bairro: Lourdes, Belo Horizonte, Minas Gerais, Brazil. brenomv@uol.com.br

International Ophthalmology

|June 1, 2011

Summary

Herpes zoster ophthalmicus can lead to optic neuritis, a rare complication. Recognizing subtle skin symptoms is crucial for early treatment of this serious condition.

Area of Science:

Ophthalmology
Neurology
Infectious Diseases

Background:

Herpes zoster (HZ) arises from varicella-zoster virus reactivation.
Herpes zoster ophthalmicus (HZO) involves inflammation of the ophthalmic branch of the trigeminal nerve.
Optic neuritis is a rare complication of HZO, occurring during or after the acute phase.

Observation:

A 74-year-old woman developed HZ optic neuritis 45 days post-trigeminal HZ.
Her initial trigeminal HZ presentation was atypical, marked only by pruritus and incompletely treated.
The optic neuritis occurred as a postherpetic complication.

Findings:

This case highlights delayed HZ optic neuritis following an atypical cutaneous presentation.
Non-specific prodromal symptoms of cutaneous HZ can precede neurological complications.

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Timely diagnosis and treatment are essential for managing HZ-related neurological sequelae.

Implications:

Emphasizes the importance of considering HZ even with subtle or atypical skin symptoms.
Underscores the need for vigilance regarding potential neurological complications like optic neuritis.
Highlights the value of prompt and appropriate treatment for prodromal HZ to prevent severe outcomes.