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Related Concept Videos

Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...

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Related Experiment Video

Updated: Jun 1, 2026

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
08:56

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

Published on: February 10, 2020

Esophageal reconstruction with colon tissue.

Takushi Yasuda1, Hitoshi Shiozaki

  • 1Department of Surgery, School of Medicine, Kinki University, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

Surgery Today
|June 1, 2011
PubMed
Summary

Best practices for esophageal reconstruction with colon tissue are reviewed. Left colon grafts offer advantages but have higher necrosis rates; microvascular anastomosis may mitigate this risk for improved outcomes.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Thoracic Surgery

Background:

  • Esophageal reconstruction using colon tissue is a complex procedure.
  • Optimal surgical techniques and graft selection remain critical for patient outcomes.
  • Current best practices require careful consideration of various factors.

Purpose of the Study:

  • To review and synthesize the current best practices for esophageal reconstruction utilizing colon tissue.
  • To evaluate the advantages and disadvantages of different colon segments and surgical routes.
  • To provide evidence-based recommendations for optimizing surgical outcomes.

Main Methods:

  • Comprehensive literature review of studies on esophageal reconstruction with colon grafts.
  • Analysis of factors influencing graft viability, including blood supply and diameter.

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An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
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Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
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Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh

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Related Experiment Videos

Last Updated: Jun 1, 2026

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
08:56

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

Published on: February 10, 2020

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
09:40

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

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  • Comparison of different surgical routes (posterior mediastinal, retrosternal, subcutaneous) and their associated risks.
  • Evaluation of techniques such as isoperistaltic reconstruction and microvascular anastomosis.

    • Main Results:

    • The left colon offers a smaller diameter and less variable blood supply but has a higher rate of graft necrosis compared to the right colon.
    • Isoperistaltic reconstruction is preferred to prevent regurgitation and improve food transit.
    • The posterior mediastinal route is shortest but carries a high risk of severe or fatal graft necrosis.
    • Retrosternal or subcutaneous routes are preferred in palliative or advanced cases, potentially requiring manubrium and clavicle resection.
    • Microvascular anastomosis can address graft ischemia but is not always necessary.

    Conclusions:

    • Colon graft selection should be flexible, based on blood supply and required length.
    • Microvascular anastomosis should be considered when graft ischemia is a risk.
    • Surgical route selection depends on the clinical scenario, balancing risks of necrosis and compression.
    • Optimizing esophageal reconstruction involves careful consideration of graft choice, reconstruction technique, and surgical pathway.