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Updated: Jun 1, 2026

Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane
Published on: April 12, 2018
Intracellular uptake of (-)epicatechin by human erythrocytes as a function of human age
Pawan Kumar Maurya1, Siya Prakash
1Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida 201303, U.P. India. pawan_biochem@yahoo.co.in
Abstract:
The present studies were carried out to determine the intracellular uptake of (-)epicatechin by erythrocytes during aging in humans. (-)Epicatechin uptake was estimated by performing ethyl acetate extraction while the total antioxidant potential of the (-)epicatechin was estimated in terms of FRAP (ferric reducing ability of plasma) values. A significant (p < 0.001) decrease in (-)epicatechin uptake by human erythrocytes was observed as a function of age. It is hypothesized that the uptake of (-)epicatechin in human erythrocytes has an important role in the regulation of PMRS (plasma membrane redox system) activity during normal human aging.
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Erythropoiesis
