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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

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Published on: February 9, 2012

Subzone based magnetic resonance elastography using a Rayleigh damped material model.

Elijah E W Van Houten¹, D vR Viviers, M D J McGarry

¹Department of Mechanical Engineering, University of Canterbury, Christchurch, Canterbury 8140, New Zealand. elijah.vanhouten@canterbury.ac.nz

Medical Physics

|June 2, 2011

Summary

This summary is machine-generated.

Rayleigh damping in magnetic resonance elastography offers a generalized model for tissue attenuation. This new method, Rayleigh composition, shows potential for differentiating tissue types, including cancerous versus healthy tissue.

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Area of Science:

Biomedical Engineering
Medical Imaging
Rheology

Background:

Magnetic resonance elastography (MRE) traditionally models soft tissue attenuation using viscoelasticity.
Viscoelastic models use a single parameter for attenuation, limiting their ability to fully characterize material behavior.

Purpose of the Study:

To introduce Rayleigh damping as a more generalized model for elastic energy attenuation in MRE.
To investigate the application of Rayleigh damping in characterizing tissue properties beyond simple stiffness.

Main Methods:

Described Rayleigh damping in the time-harmonic case, contrasting it with viscoelastic models.
Conducted MRE studies on gelatin and tofu phantoms, and preliminary in vivo breast data using subzone-based Rayleigh damped elastography.

Main Results:

Identified a distinct 'Rayleigh composition' parameter that varies between different material types.
Observed lower Rayleigh composition values in tofu and healthy tissue compared to gelatin and cancerous tissue.

Conclusions:

Rayleigh damping elastography and Rayleigh composition imaging may offer a method to differentiate tissue structures.
This technique could enhance MRE's diagnostic capabilities by providing information on elastic stiffness, attenuation, and tissue composition.