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Related Experiment Video

Updated: Jun 1, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

[Bacterial endogenous endophthalmitis].

Luisa Valle¹, M Camba, F Fernández

¹Serviço de Medicina Interna, Hospital Povisa (Vigo), Spain.

Acta Medica Portuguesa

|June 2, 2011

Summary

Endogenous bacterial endophthalmitis, an uncommon eye infection from bloodstream bacteria, can lead to blindness. This case highlights a diabetic patient with Escherichia coli endophthalmitis requiring eye removal.

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Area of Science:

Ophthalmology
Infectious Diseases
Bacteriology

Background:

Endogenous bacterial endophthalmitis is a rare but severe intraocular infection.
It arises from hematogenous spread from a distant septic focus.
Prompt diagnosis and treatment are crucial to prevent vision loss.

Observation:

A case of endogenous endophthalmitis in a diabetic patient is presented.
The infection originated from Escherichia coli bacteremia, likely from a urinary tract source.
The patient experienced a poor visual outcome despite medical intervention.

Findings:

Escherichia coli bacteremia can lead to severe endogenous endophthalmitis.
Diabetic patients are at increased risk for such infections.
The clinical course can be aggressive, resulting in significant vision impairment.

Implications:

This case underscores the importance of considering endogenous endophthalmitis in diabetic patients with sepsis.
Early recognition and aggressive management are vital to preserve vision.
Urinary tract infections are a significant potential source for E. coli endophthalmitis.