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Motoring ahead with rodents.

Bence P Ölveczky1

  • 1Harvard University, Department of Organismic and Evolutionary Biology and Center for Brain Science, 52 Oxford Street, Cambridge, MA 02138, United States. olveczky@fas.harvard.edu

Current Opinion in Neurobiology
|June 2, 2011
PubMed
Summary

Rodents are increasingly valuable models for studying motor learning. Their genetic tools and trainability offer new insights into neural circuits controlling learned movements.

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Area of Science:

  • Neuroscience
  • Behavioral Neuroscience
  • Motor Control

Background:

  • Traditionally, monkeys and songbirds were primary models for motor learning research.
  • Rodents offer advantages due to genetic tools and ease of training for motor tasks.

Purpose of the Study:

  • To discuss the utility of rodents in studying neural circuits of motor learning.
  • To review current research trends and outcomes in rodent motor learning.
  • To propose strategies for expanding rodent use in complex motor learning studies.

Main Methods:

  • Review of existing literature on rodent models for motor learning.
  • Analysis of genetic tools and transgenic animal availability.
  • Assessment of rodent trainability for diverse motor tasks.

Main Results:

  • Rodents provide a powerful platform for dissecting neural circuits underlying motor skill acquisition.
  • Recent advancements highlight the potential of rodents in complex motor learning research.
  • Challenges and benefits of using rodents are discussed.

Conclusions:

  • Rodents are emerging as a key model system for understanding the neural basis of learned motor behaviors.
  • Further development and adoption of rodent models will advance the field of motor learning research.

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